STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61729.1PFAM: Glutaredoxin; InterPro IPR002109; KEGG: sta:STHERM_c06810 hypothetical protein; PFAM: Glutaredoxin; SPTR: Glutaredoxin. (159 aa)    
Predicted Functional Partners:
AEJ61728.1
PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR005144:IPR012833; KEGG: sta:STHERM_c06820 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic.
     0.974
AEJ61730.1
PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR012840; KEGG: sta:STHERM_c06800 hypothetical protein; PFAM: Radical SAM; SPTR: Anaerobic ribonucleoside-triphosphate reductase activating protein; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic-like.
 
  
 0.939
nrdR
Transcriptional repressor nrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
     
 0.720
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.479
AEJ61726.1
PFAM: ArsC family; COGs: COG1393 Arsenate reductase and related protein glutaredoxin family; InterPro IPR006660; KEGG: sta:STHERM_c06840 hypothetical protein; PFAM: Arsenate reductase-like; SPTR: Arsenate reductase; Belongs to the ArsC family.
       0.472
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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