STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61743.1Cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: sta:STHERM_c13440 hypothetical protein; PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein. (294 aa)    
Predicted Functional Partners:
AEJ61058.1
ABC-type transporter, integral membrane subunit; PFAM: Cobalt transport protein; InterPro IPR003339; KEGG: sta:STHERM_c14490 hypothetical protein; PFAM: Cobalt transport protein; SPTR: Cobalt transport protein.
  
 
 0.945
AEJ61059.1
PFAM: ABC transporter; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c14480 membrane associated ATPase; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 
 0.821
AEJ62175.1
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; PFAM: AIR carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: sta:STHERM_c18730 hypothetical protein; PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase.
 
    0.764
AEJ62176.1
Conserved hypothetical protein CHP00268; PFAM: NAD synthase; TIGRFAM: TIGR00268 family protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR001962:IPR005232; KEGG: sta:STHERM_c18740 hypothetical protein; PFAM: Asparagine synthase; SPTR: Asparagine synthase; TIGRFAM: Conserved hypothetical protein CHP00268.
 
    0.731
AEJ62177.1
PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; COGs: COG1641 conserved hypothetical protein; HAMAP: UPF0272 protein; InterPro IPR002822; KEGG: dma:DMR_16560 hypothetical protein; PFAM: Protein of unknown function DUF111; SPTR: Putative uncharacterized protein; TIGRFAM: Protein of unknown function DUF111; Belongs to the LarC family.
 
    0.571
AEJ61934.1
uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...]
  
  
 0.461
AEJ60665.1
PFAM: Uncharacterized conserved protein (DUF2088); COGs: COG3875 conserved hypothetical protein; KEGG: sta:STHERM_c04160 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.456
AEJ61744.1
MULE transposase, conserved domain-containing protein; PFAM: Transposase, Mutator family; COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR018289; KEGG: sta:STHERM_c00050 transposase for insertion sequence element ISRM5; PFAM: MULE transposase, conserved domain; SPTR: MULE transposase, conserved domain.
       0.431
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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