STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61749.1PFAM: Cupin domain; COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR013096; KEGG: sta:STHERM_c13500 cupin 2, conserved barrel domain-containing protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin 2 conserved barrel domain protein. (107 aa)    
Predicted Functional Partners:
AEJ62011.1
PFAM: Alginate lyase; InterPro IPR014895; KEGG: cpy:Cphy_0492 alginate lyase 2; PFAM: Alginate lyase 2; SPTR: Alginate lyase 2.
  
   
 0.603
AEJ61748.1
Hypothetical protein.
       0.556
AEJ62008.1
PFAM: Heparinase II/III-like protein; InterPro IPR012480; KEGG: gym:GYMC10_3686 heparinase II/III family protein; PFAM: Heparinase II/III-like; SPTR: Heparinase II/III family protein.
 
   
 0.551
AEJ62404.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR003313:IPR000005:IPR018060; KEGG: sta:STHERM_c21040 transcriptional regulatory protein; PFAM: AraC protein, arabinose-binding/dimerisation; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
  
 
 0.519
AEJ61750.1
TRAP dicarboxylate transporter, DctP subunit; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR018389:IPR004682; KEGG: sta:STHERM_c13510 transporter; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: TRAP dicarboxylate transporter, DctP subunit; TIGRFAM: TRAP dicarboxylate transporter, DctP subunit.
       0.517
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
  
 
 0.417
AEJ61751.1
PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; COGs: COG3090 TRAP-type C4-dicarboxylate transport system small permease component; InterPro IPR007387; KEGG: sta:STHERM_c13520 hypothetical protein; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: Tripartite ATP-independent periplasmic transporter DctQ component.
       0.405
AEJ61752.1
PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR010656:IPR004681; KEGG: sta:STHERM_c13530 transporter; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit.
       0.404
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.