STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61757.1PFAM: Protein of unknown function (DUF2807); KEGG: sta:STHERM_c13580 hypothetical protein; SPTR: Putative uncharacterized protein. (231 aa)    
Predicted Functional Partners:
AEJ61758.1
PFAM: Bacterial regulatory proteins, gntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: sta:STHERM_c13590 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family.
       0.796
AEJ61760.1
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c13610 ABC transporter ATP binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
  
    0.779
AEJ61759.1
KEGG: sta:STHERM_c13600 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ62037.1
Pentapeptide repeat protein; COGs: COG1357 Uncharacterized low-complexity protein; InterPro IPR001646; KEGG: sta:STHERM_c17050 pentapeptide protein; PFAM: Pentapeptide repeat; SPTR: Pentapeptide repeat protein.
   
   0.601
AEJ62146.1
Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain; LysM domain; InterPro IPR008258:IPR018392:IPR002482; KEGG: sta:STHERM_c18450 transglycosylase, SLT family; PFAM: Lytic transglycosylase-like, catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Lytic transglycosylase catalytic.
   
   0.596
AEJ61761.1
KEGG: sta:STHERM_c13620 hypothetical protein; SPTR: Putative alkylmercury lyase.
       0.524
AEJ61980.1
OmpA/MotB domain protein; PFAM: OmpA family; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: sta:STHERM_c16610 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA/MotB domain protein.
  
 
   0.514
AEJ62092.1
PFAM: Histidine kinase; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3920 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR011495:IPR003594:IPR 000014; KEGG: sta:STHERM_c17620 sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; PAS fold; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; SMART: Signal transduction response regulator, receiver region; PAS; ATP-binding [...]
 
  
 0.501
AEJ60333.1
PFAM: PspA/IM30 family; COGs: COG1842 Phage shock protein A (IM30) suppresses sigma54-dependent transcription; InterPro IPR007157; KEGG: sta:STHERM_c00460 phage shock protein A-like protein; PFAM: PspA/IM30; SPTR: Phage shock protein A, PspA.
  
  
 0.469
AEJ62248.1
PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box; COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594:IPR000014; KEGG: sta:STHERM_c19440 sensory box histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; ATP-binding region, ATPase-like; SPTR: Signal transduction histidine kinase; TIGRFAM: PAS.
 
  
 0.459
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.