STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61770.1Hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR013352; KEGG: sta:STHERM_c13740 hypothetical protein; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulp [...] (583 aa)    
Predicted Functional Partners:
AEJ61771.1
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575:IPR001450; KEGG: sta:STHERM_c13750 hypothetical protein; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4 [...]
 
 
 0.996
AEJ61774.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: sta:STHERM_c13780 hypothetical protein; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; SPTR: NAD(P)-dependent iron-only hydrogenase diaphorase component iron-sulfur protein.
 
 0.993
AEJ61772.1
KEGG: sta:STHERM_c13760 hypothetical protein; SPTR: NADP-reducing hydrogenase, subunit B.
 
 
 0.983
AEJ60919.1
PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575; KEGG: sta:STHERM_c06250 NADH-quinone oxidoreductase subunit 1; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: NADH dehydrogenase (Quinone).
 
 
 0.963
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
 
 0.953
AEJ60918.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: sta:STHERM_c06240 NADH-quinone oxidoreductase subunit E; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; SPTR: NADH-quinone oxidoreductase, E subunit; TIGRFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit.
 
 
 0.920
AEJ61540.1
Hypothetical protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; KEGG: sta:STHERM_c12370 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.919
AEJ61537.1
Hypothetical protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; KEGG: sta:STHERM_c12340 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.915
AEJ61866.1
PFAM: Domain of unknown function (DUF362); COGs: COG2006 conserved hypothetical protein; InterPro IPR007160:IPR001450; KEGG: sta:STHERM_c15570 iron-sulfur cluster-binding protein; PFAM: Protein of unknown function DUF362; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein.
  
 
 0.912
AEJ60609.1
PFAM: 4Fe-4S binding domain; InterPro IPR001450; KEGG: ssm:Spirs_3066 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
 
 0.866
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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