STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61778.1Hypothetical protein; PFAM: DRTGG domain; KEGG: sta:STHERM_c13820 hypothetical protein; SPTR: Putative uncharacterized protein. (113 aa)    
Predicted Functional Partners:
AEJ61777.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG2524 transcriptional regulator protein; InterPro IPR000644:IPR003594; KEGG: sta:STHERM_c13810 transcriptional regulatory protein; PFAM: Cystathionine beta-synthase, core; ATP-binding region, ATPase-like; SMART: Cystathionine beta-synthase, core; SPTR: Putative signal transduction protein with CBS domains.
 
     0.956
AEJ61779.1
PFAM: PHP domain; COGs: COG1379 conserved hypothetical protein; InterPro IPR003141:IPR004013; KEGG: sta:STHERM_c13830 PHP-like protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein.
 
     0.955
AEJ61776.1
PFAM: DRTGG domain; InterPro IPR010766; KEGG: sta:STHERM_c13800 hypothetical protein; PFAM: DRTGG; SPTR: DRTGG domain protein.
 
     0.951
AEJ61772.1
KEGG: sta:STHERM_c13760 hypothetical protein; SPTR: NADP-reducing hydrogenase, subunit B.
 
     0.874
AEJ61773.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594; KEGG: sta:STHERM_c13770 histidine kinase; PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Histidine kinase.
 
     0.812
rex-3
Redox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.658
AEJ61771.1
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575:IPR001450; KEGG: sta:STHERM_c13750 hypothetical protein; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4 [...]
 
   
 0.642
AEJ61770.1
Hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR013352; KEGG: sta:STHERM_c13740 hypothetical protein; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulp [...]
 
   
 0.608
AEJ61774.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: sta:STHERM_c13780 hypothetical protein; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; SPTR: NAD(P)-dependent iron-only hydrogenase diaphorase component iron-sulfur protein.
 
     0.535
AEJ61538.1
PFAM: Stage II sporulation protein E (SpoIIE); InterPro IPR010822; KEGG: sta:STHERM_c12350 hypothetical protein; PFAM: Sporulation stage II, protein E C-terminal; SPTR: Putative uncharacterized protein.
  
     0.521
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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