STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61785.1PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c13860 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. (341 aa)    
Predicted Functional Partners:
AEJ61321.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit.
    
 
 0.680
AEJ61786.1
PFAM: Glycosyl hydrolases family 16; COGs: COG2273 Beta-glucanase/Beta-glucan synthetase; InterPro IPR000757; KEGG: sta:STHERM_c13870 glycoside hydrolase, family 16; PFAM: Glycoside hydrolase, family 16; SPTR: Glycoside hydrolase family 16.
 
     0.578
AEJ61784.1
KEGG: sta:STHERM_c13850 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.570
AEJ62498.1
Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein.
   
 
 0.545
AEJ61783.1
PFAM: Glycosyl hydrolases family 16; Carbohydrate binding domain; COGs: COG2273 Beta-glucanase/Beta-glucan synthetase; InterPro IPR003305:IPR000757; KEGG: sta:STHERM_c13840 laminarinase; PFAM: Glycoside hydrolase, family 16; Carbohydrate-binding, CenC-like; SPTR: Glucan endo-1,3-beta-D-glucosidase.
 
     0.493
AEJ61787.1
PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c13890 glucose-resistance amylase regulator; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family.
 
    
0.432
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.429
AEJ61782.1
Laminarinase; KEGG: sta:STHERM_c13840 laminarinase; SPTR: Putative uncharacterized protein.
       0.405
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.