Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61786.1PFAM: Glycosyl hydrolases family 16; COGs: COG2273 Beta-glucanase/Beta-glucan synthetase; InterPro IPR000757; KEGG: sta:STHERM_c13870 glycoside hydrolase, family 16; PFAM: Glycoside hydrolase, family 16; SPTR: Glycoside hydrolase family 16. (367 aa)    
Predicted Functional Partners:
AEJ61784.1
KEGG: sta:STHERM_c13850 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.688
AEJ61792.1
PFAM: O-Glycosyl hydrolase family 30; COGs: COG5520 O-Glycosyl hydrolase; InterPro IPR001139; KEGG: fno:Fnod_0296 glucan endo-1,6-beta-glucosidase; PFAM: Glycoside hydrolase, family 30; SPTR: Glucan endo-1,6-beta-glucosidase; manually curated; Belongs to the glycosyl hydrolase 30 family.
 
   
 0.602
AEJ61785.1
PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c13860 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family.
 
     0.575
AEJ60366.1
PFAM: F5/8 type C domain; Cellulase (glycosyl hydrolase family 5); InterPro IPR000421; KEGG: sta:STHERM_c00920 hypothetical protein; PFAM: Coagulation factor 5/8 type, C-terminal; SPTR: Mannan endo-1,4-beta-mannosidase.
 
     0.570
AEJ61787.1
PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c13890 glucose-resistance amylase regulator; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family.
 
     0.534
AEJ61831.1
PFAM: F5/8 type C domain; Carbohydrate binding module (family 6); CARDB; InterProIPR000421:IPR006584:IPR006626:IPR011635:IPR 005084; KEGG: sur:STAUR_0436 secreted glycosyl hydrolase; PFAM: Coagulation factor 5/8 type, C-terminal; APHP; Carbohydrate binding domain, family 6; SMART: Cellulose binding, type IV; Coagulation factor 5/8 type, C-terminal; Parallel beta-helix repeat; SPTR: Coagulation factor 5/8 type domain protein.
  
     0.507
AEJ61045.1
Hypothetical protein; PFAM: Esterase PHB depolymerase; COGs: COG4099 peptidase; KEGG: sta:STHERM_c14610 hypothetical protein; SPTR: Peptidase.
  
     0.503
AEJ62054.1
PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764:IPR002772; KEGG: sta:STHERM_c17240 glycoside hydrolase; PFAM: Glycoside hydrolase, family 3, N-terminal; Glycoside hydrolase, family 3, C-terminal; SPTR: Glycoside hydrolase family 3 domain protein.
 
  
 0.451
AEJ61964.1
PFAM: Glycosyl hydrolase family 9; Carbohydrate binding domain; N-terminal ig-like domain of cellulase; InterPro IPR003305:IPR004197:IPR001701; KEGG: sta:STHERM_c16430 cellodextrinase; PFAM: Glycoside hydrolase, family 9; Carbohydrate-binding, CenC-like; Glycoside hydrolase, family 9, N-terminal, Ig-like; SPTR: Glycoside hydrolase family 9.
 
   
 0.448
AEJ61028.1
PFAM: Glycosyl hydrolases family 43; InterPro IPR006710; KEGG: sta:STHERM_c14740 hypothetical protein; PFAM: Glycoside hydrolase, family 43; SPTR: Alpha-N-arabinofuranosidase.
 
   
 0.434
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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