Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61798.1PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: sta:STHERM_c13990 alpha-glucosidase; PFAM: Glycoside hydrolase, family 4; SPTR: Glycoside hydrolase family 4. (473 aa)    
Predicted Functional Partners:
AEJ61797.1
Carbohydrate-binding CenC domain protein; PFAM: Carbohydrate binding domain; InterPro IPR003305; KEGG: sta:STHERM_c13980 hypothetical protein; PFAM: Carbohydrate-binding, CenC-like; SPTR: Carbohydrate-binding CenC domain protein.
       0.773
AEJ60762.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: dtu:Dtur_1732 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family.
 
     0.653
AEJ61445.1
Hypothetical protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; KEGG: tma:TM1174 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.609
AEJ60646.1
Glycoside hydrolase clan GH-D; PFAM: Melibiase; COGs: COG3345 Alpha-galactosidase; InterPro IPR000111; KEGG: sta:STHERM_c03960 alpha-galactosidase; PFAM: Glycoside hydrolase, clan GH-D; SPTR: Glycoside hydrolase clan GH-D.
 
   
 0.579
pcm
Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
       0.546
AEJ61027.1
PFAM: 3-dehydroquinate synthase; COGs: COG0371 Glycerol dehydrogenase; InterPro IPR002658; KEGG: sta:STHERM_c14750 glycerol-1-phosphate dehydrogenase; PFAM: 3-dehydroquinate synthase AroB; SPTR: Glycerol-1-phosphate dehydrogenase (NAD(P)(+)).
  
    0.522
AEJ61010.1
PFAM: DsrE/DsrF-like family; TIGRFAM: sulfur relay protein TusD/DsrE; COGs: COG1553 conserved hypothetical protein involved in intracellular sulfur reduction; InterPro IPR003787; KEGG: tna:CTN_1597 DsrE family protein; PFAM: Sulphur relay, DsrE-like protein; SPTR: DsrE family protein.
  
     0.446
trmH
tRNA/rRNA methyltransferase (SpoU); Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.442
AEJ61011.1
PFAM: YeeE/YedE family (DUF395); InterPro IPR007272; KEGG: tle:Tlet_1313 protein of unknown function DUF395 YeeE/YedE; PFAM: Protein of unknown function DUF395, YeeE/YedE; SPTR: Putative uncharacterized protein.
  
     0.426
AEJ62021.1
PFAM: ABC-2 type transporter; COGs: COG1668 ABC-type Na+ efflux pump permease component; InterPro IPR013525; KEGG: sta:STHERM_c16880 ABC-2 type transporter family; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
     0.425
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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