STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61827.1PFAM: Glycosyl hydrolase family 65, C-terminal domain; Glycosyl hydrolase family 65 central catalytic domain; Glycosyl hydrolase family 65, N-terminal domain; COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196:IPR005195:IPR005194; KEGG: sta:STHERM_c15330 kojibiose phosphorylase; PFAM: Glycoside hydrolase family 65, central catalytic; Glycoside hydrolase family 65, N-terminal; Glycoside hydrolase, family 65, C-terminal; SPTR: Glycoside hydrolase family 65 central catalytic. (772 aa)    
Predicted Functional Partners:
AEJ61825.1
Beta-phosphoglucomutase; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: beta-phosphoglucomutase family hydrolase; beta-phosphoglucomutase; haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR010972:IPR010976:IPR006402:IPR005834; KEGG: sta:STHERM_c15310 hypothetical protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Beta-phosphoglucomutase; TIGRFAM: Beta-phosphoglucomutase; Beta-phosphoglucomutase hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3.
 
 0.999
AEJ61316.1
PFAM: Glycosyl hydrolases family 31; COGs: COG1501 Alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: sta:STHERM_c10190 alpha-glucosidase 2; PFAM: Glycoside hydrolase, family 31; SPTR: Alpha-glucosidase.
 
  
  0.920
AEJ61918.1
PFAM: Alpha-amylase C-terminal beta-sheet domain; Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006589:IPR012850:IPR006047; KEGG: sta:STHERM_c15980 alpha-amylase type A isozyme precursor; PFAM: Glycosyl hydrolase, family 13, catalytic region; Alpha-amylase, C-terminal beta-sheet; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; Alpha-amylase, C-terminal beta-sheet; SPTR: Alpha amylase catalytic region.
  
 
 0.909
AEJ61553.1
Glycoside hydrolase family 57; PFAM: Domain of unknown function (DUF1925); Glycosyl hydrolase family 57; Domain of unknown function (DUF1926); InterPro IPR004300:IPR015179; KEGG: sta:STHERM_c12500 alpha-amylase 1; PFAM: Glycoside hydrolase, family 57, core; Alpha-amylase/4-alpha-glucanotransferase, prokaryotic; SPTR: Glycoside hydrolase family 57.
     
  0.900
AEJ61826.1
PFAM: Glycosyl hydrolase family 65 central catalytic domain; Glycosyl hydrolase family 65, N-terminal domain; COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196:IPR005195; KEGG: sta:STHERM_c15320 kojibiose phosphorylase; PFAM: Glycoside hydrolase family 65, central catalytic; Glycoside hydrolase family 65, N-terminal; SPTR: Glycoside hydrolase family 65 central catalytic.
 
    
0.831
AEJ61081.1
HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR006402:IPR005834; KEGG: sta:STHERM_c14260 GS1-like protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3.
 
  
 0.710
AEJ61824.1
Hypothetical protein; PFAM: Glycosyl hydrolase family 71; KEGG: sta:STHERM_c15300 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.637
AEJ61829.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c15350 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 1, CUT1 family.
  
  
 0.565
AEJ61828.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c15340 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family.
       0.536
AEJ61830.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c15360 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family.
 
   
 0.524
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.