STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61831.1PFAM: F5/8 type C domain; Carbohydrate binding module (family 6); CARDB; InterProIPR000421:IPR006584:IPR006626:IPR011635:IPR 005084; KEGG: sur:STAUR_0436 secreted glycosyl hydrolase; PFAM: Coagulation factor 5/8 type, C-terminal; APHP; Carbohydrate binding domain, family 6; SMART: Cellulose binding, type IV; Coagulation factor 5/8 type, C-terminal; Parallel beta-helix repeat; SPTR: Coagulation factor 5/8 type domain protein. (1043 aa)    
Predicted Functional Partners:
AEJ61551.1
PFAM: Cellulase (glycosyl hydrolase family 5); InterPro IPR001547; KEGG: sta:STHERM_c12480 cellulase, glycosyl hydrolase family 5; PFAM: Glycoside hydrolase, family 5; SPTR: Mannan endo-1,4-beta-mannosidase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.738
AEJ60657.1
Glycosyl hydrolase BNR repeat-containing protein; PFAM: BNR/Asp-box repeat; InterPro IPR002860; KEGG: cth:Cthe_1398 cellulosome enzyme, dockerin type I; PFAM: BNR repeat; SPTR: Cellulosome enzyme, dockerin type I; manually curated.
  
     0.714
AEJ61830.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c15360 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family.
 
     0.691
AEJ60366.1
PFAM: F5/8 type C domain; Cellulase (glycosyl hydrolase family 5); InterPro IPR000421; KEGG: sta:STHERM_c00920 hypothetical protein; PFAM: Coagulation factor 5/8 type, C-terminal; SPTR: Mannan endo-1,4-beta-mannosidase.
  
     0.650
AEJ60658.1
PFAM: Glycosyl hydrolase family 12; InterPro IPR002594; KEGG: sta:STHERM_c04060 glycosyl hydrolase family 12 protein, TPS linker, domain X; PFAM: Glycoside hydrolase, family 12; SPTR: Glycoside hydrolase family 12; Belongs to the glycosyl hydrolase 12 (cellulase H) family.
  
     0.635
AEJ61964.1
PFAM: Glycosyl hydrolase family 9; Carbohydrate binding domain; N-terminal ig-like domain of cellulase; InterPro IPR003305:IPR004197:IPR001701; KEGG: sta:STHERM_c16430 cellodextrinase; PFAM: Glycoside hydrolase, family 9; Carbohydrate-binding, CenC-like; Glycoside hydrolase, family 9, N-terminal, Ig-like; SPTR: Glycoside hydrolase family 9.
  
     0.634
AEJ62364.1
Glycoside hydrolase family 9; PFAM: Cellulose binding domain; Glycosyl hydrolase family 9; InterPro IPR001701:IPR001956; KEGG: sta:STHERM_c20630 glycoside hydrolase family 9, CBM3, linker, domain X; PFAM: Glycoside hydrolase, family 9; Bacterial type 3a, cellulose-binding; SPTR: Cellulase.
  
     0.589
AEJ60991.1
PFAM: Glycosyl hydrolase family 10; COGs: COG3693 Beta-1 4-xylanase; InterPro IPR001000; KEGG: sta:STHERM_c15090 endo-1,4-beta-xylanase B; PFAM: Glycoside hydrolase, family 10; SMART: Glycoside hydrolase, family 10; SPTR: Endo-1,4-beta-xylanase.
  
     0.583
AEJ62365.1
PFAM: Cellulase (glycosyl hydrolase family 5); COGs: COG2730 Endoglucanase; InterPro IPR001547; KEGG: sta:STHERM_c20620 cellulase, glycosyl hydrolase family 5, TPS linker, domain X; PFAM: Glycoside hydrolase, family 5; SPTR: Glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
     0.564
AEJ62197.1
PFAM: Glycosyl hydrolase family 10; COGs: COG3693 Beta-1 4-xylanase; InterPro IPR001000; KEGG: sta:STHERM_c18930 endo-1,4-beta-xylanase B precursor; PFAM: Glycoside hydrolase, family 10; SMART: Glycoside hydrolase, family 10; SPTR: Endo-1,4-beta-xylanase.
  
     0.551
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.