Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61842.1PFAM: Type IV leader peptidase family; InterPro IPR000045; KEGG: tna:CTN_0883 type IV prepilin peptidase; PFAM: Peptidase A24A, prepilin type IV; SPTR: Peptidase A24A prepilin type IV. (155 aa)    
Predicted Functional Partners:
AEJ61838.1
PFAM: Bacterial type II secretion system protein G; TIGRFAM: general secretion pathway protein G; COGs: COG2165 Type II secretory pathway pseudopilin PulG; InterPro IPR012902:IPR010054:IPR013545; KEGG: general secretion pathway protein G; PFAM: Type II secretion system protein G; SPTR: General secretion pathway protein G; TIGRFAM: General secretion pathway protein G; Prepilin-type cleavage/methylation, N-terminal.
  
  
 0.835
AEJ61839.1
PFAM: Bacterial type II secretion system protein F domain; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: tam:Theam_0991 type II secretion system F domain protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system F domain.
  
  
 0.830
AEJ61201.1
PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: sta:STHERM_c09020 DNA processing protein DprA; PFAM: DNA recombination-mediator protein A; SPTR: DNA protecting protein DprA; TIGRFAM: DNA recombination-mediator protein A.
  
  
 0.810
AEJ61840.1
PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein; COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831:IPR001482; KEGG: cle:Clole_1716 type II secretion system protein E; PFAM: Type II secretion system protein E; General secretory system II, protein E, N-terminal; SPTR: Type II secretion system protein E.
  
 
 0.799
AEJ61841.1
PFAM: Bacterial type II and III secretion system protein; COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR004846; KEGG: type II and III secretion system protein; PFAM: Type II/III secretion system; SPTR: Type II and III secretion system protein; Belongs to the bacterial secretin family.
  
  
 0.694
AEJ61843.1
PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: sta:STHERM_c15370 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer.
     
 0.574
AEJ61572.1
PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein; COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: sta:STHERM_c08650 hypothetical protein; PFAM: ComEC/Rec2-related protein; SPTR: ComEC/Rec2-related protein; TIGRFAM: ComEC/Rec2-related protein.
  
  
 0.547
aroE
3-dehydroquinate dehydratase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.542
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.496
AEJ61400.1
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
   
    0.487
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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