Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61854.1CoA-substrate-specific enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase, putative; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275:IPR002731:IPR018709; KEGG: sta:STHERM_c15510 hypothetical protein; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase, BadF/BadG/BcrA/BcrD type; SPTR: CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase. (1476 aa)    
Predicted Functional Partners:
AEJ61855.1
MULE transposase, conserved domain-containing protein; Required for the transposition of the insertion element.
       0.635
AEJ60922.1
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
 
     0.444
AEJ61852.1
KEGG: sta:STHERM_c15470 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.402
AEJ61853.1
KEGG: sta:STHERM_c15490 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.402
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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