Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fclNAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (369 aa)    
Predicted Functional Partners:
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
 0.998
AEJ61877.1
PFAM: Glycosyl transferase family 2; COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: sta:STHERM_c15710 hypothetical protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2.
 
  
 0.805
AEJ61882.1
PFAM: Polysaccharide biosynthesis protein; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: cly:Celly_2621 polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein.
 
  
 0.785
AEJ61885.1
PFAM: Glycosyl transferases group 1; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sta:STHERM_c15750 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1.
  
  
 0.750
AEJ61879.1
PFAM: Glycosyl transferase family 2; KEGG: dba:Dbac_3282 sugar transferase; SPTR: Sugar transferase.
 
  
 0.746
AEJ61886.1
PFAM: HEPN domain; InterPro IPR007842; KEGG: sta:STHERM_c15560 hypothetical protein; PFAM: HEPN; SPTR: HEPN domain protein.
       0.737
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.707
AEJ61878.1
PFAM: Glycosyl transferases group 1; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sta:STHERM_c15720 glycosyl transferase, group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1.
 
  
 0.701
rpsC
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
  0.689
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.672
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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