STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (378 aa)    
Predicted Functional Partners:
fcl
NAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.998
AEJ60450.1
PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: sta:STHERM_c01790 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; SPTR: Mannose-1-phosphate guanylyltransferase.
 
 
 0.944
AEJ61180.1
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sta:STHERM_c08820 aminotransferase, DegT/DnrJ/EryC1/StrS family; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.
  
 
 0.917
AEJ61888.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017475:IPR003362; KEGG: tth:TTC0275 undecaprenyl-phosphate galactosephosphotransferase; PFAM: Bacterial sugar transferase; SPTR: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
  
  
 0.858
AEJ61885.1
PFAM: Glycosyl transferases group 1; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sta:STHERM_c15750 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1.
  
  
 0.795
AEJ61882.1
PFAM: Polysaccharide biosynthesis protein; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: cly:Celly_2621 polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein.
 
  
 0.781
AEJ61886.1
PFAM: HEPN domain; InterPro IPR007842; KEGG: sta:STHERM_c15560 hypothetical protein; PFAM: HEPN; SPTR: HEPN domain protein.
       0.773
AEJ61620.1
PFAM: Polysaccharide biosynthesis protein; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: sta:STHERM_c08150 capsular polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: Polysaccharide biosynthesis protein CapD.
  
  
 0.738
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
 
      0.704
AEJ61877.1
PFAM: Glycosyl transferase family 2; COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: sta:STHERM_c15710 hypothetical protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2.
 
  
 0.699
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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