Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61897.1Soluble ligand binding domain-containing protein; PFAM: SLBB domain; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR019554; KEGG: sta:STHERM_c15850 polysaccharide biosynthesis protein; PFAM: Soluble ligand binding domain; SPTR: Soluble ligand binding domain. (482 aa)    
Predicted Functional Partners:
AEJ61871.1
Lipopolysaccharide biosynthesis protein; PFAM: Chain length determinant protein; COGs: COG3524 Capsule polysaccharide export protein; InterPro IPR003856; KEGG: sta:STHERM_c15650 hypothetical protein; PFAM: Lipopolysaccharide biosynthesis; SPTR: Lipopolysaccharide biosynthesis protein.
 
 
 0.971
AEJ61888.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017475:IPR003362; KEGG: tth:TTC0275 undecaprenyl-phosphate galactosephosphotransferase; PFAM: Bacterial sugar transferase; SPTR: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
  
  
 0.809
AEJ60986.1
PFAM: Dinitrogenase iron-molybdenum cofactor; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: sta:STHERM_c15140 hypothetical protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Putative uncharacterized protein; manually curated.
  
 
 0.696
AEJ62141.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
 
 0.671
AEJ61620.1
PFAM: Polysaccharide biosynthesis protein; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: sta:STHERM_c08150 capsular polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: Polysaccharide biosynthesis protein CapD.
  
  
 0.669
AEJ61879.1
PFAM: Glycosyl transferase family 2; KEGG: dba:Dbac_3282 sugar transferase; SPTR: Sugar transferase.
 
  
 0.560
AEJ60450.1
PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: sta:STHERM_c01790 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; SPTR: Mannose-1-phosphate guanylyltransferase.
  
  
 0.452
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.442
AEJ61896.1
RNP-1 like RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: sta:STHERM_c15840 RNA-binding region RNP-1; PFAM: RNA recognition motif, RNP-1; SMART: RNA recognition motif, RNP-1; SPTR: RNA-binding region RNP-1.
       0.427
AEJ61221.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
    
   0.425
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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