Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61907.1PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: sta:STHERM_c04230 hypothetical protein; PFAM: HTH transcriptional regulator, GntR; GntR, C-terminal; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family. (235 aa)    
Predicted Functional Partners:
AEJ60913.1
GntR domain protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG2186 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: sta:STHERM_c06190 transcriptional regulatory protein; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: GntR domain protein.
 
  
 0.781
AEJ61908.1
Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: rha:RHA1_ro08212 NADH-dependent oxidoreductase; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein.
       0.601
AEJ61906.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: ote:Oter_1273 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: 5-keto-D-gluconate 5-reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.577
AEJ61909.1
PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR004681:IPR010656; KEGG: bcl:ABC4044 TRAP-type transport system permease large protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit.
  
    0.551
AEJ60909.1
PFAM: Tripartite tricarboxylate transporter family receptor; COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: sta:STHERM_c06150 tricarboxylic transport; SPTR: Tricarboxylate-binding protein.
 
     0.491
AEJ62049.1
PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR004789:IPR002912:IPR019455; KEGG: sta:STHERM_c17180 acetolate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit.
   
    0.440
AEJ60911.1
Protein of unknown function DUF112 transmembrane; PFAM: Tripartite tricarboxylate transporter TctA family; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: sta:STHERM_c06170 hypothetical protein; PFAM: Protein of unknown function DUF112, transmembrane; SPTR: Putative uncharacterized protein.
 
     0.426
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.