Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEJ61908.1Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: rha:RHA1_ro08212 NADH-dependent oxidoreductase; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein. (326 aa)    
Predicted Functional Partners:
AEJ61909.1
PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR004681:IPR010656; KEGG: bcl:ABC4044 TRAP-type transport system permease large protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit.
       0.691
AEJ61907.1
PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: sta:STHERM_c04230 hypothetical protein; PFAM: HTH transcriptional regulator, GntR; GntR, C-terminal; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family.
       0.601
AEJ61621.1
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sta:STHERM_c08130 spore coat polysaccharide biosynthesis protein C; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.573
AEJ61910.1
Transposase-like protein; COGs: COG3676 Transposase and inactivated derivatives; KEGG: rmr:Rmar_2140 transposase-like protein; SPTR: Transposase-like protein.
       0.483
AEJ61906.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: ote:Oter_1273 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: 5-keto-D-gluconate 5-reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.474
AEJ61180.1
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sta:STHERM_c08820 aminotransferase, DegT/DnrJ/EryC1/StrS family; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.437
AEJ60648.1
PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; COGs: COG0153 Galactokinase; InterPro IPR000705:IPR019539:IPR006204:IPR013750; KEGG: sta:STHERM_c03980 galactokinase; PFAM: GHMP kinase; Galactokinase galactose-binding domain; GHMP kinase, C-terminal; SPTR: Galactokinase; TIGRFAM: Galactokinase.
  
 
 0.400
AEJ61164.1
PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; COGs: COG0153 Galactokinase; InterPro IPR019539:IPR006204:IPR013750; KEGG: sta:STHERM_c12660 hypothetical protein; PFAM: GHMP kinase; Galactokinase galactose-binding domain; GHMP kinase, C-terminal; SPTR: Galactokinase.
  
 
 0.400
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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