Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEJ61918.1PFAM: Alpha-amylase C-terminal beta-sheet domain; Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006589:IPR012850:IPR006047; KEGG: sta:STHERM_c15980 alpha-amylase type A isozyme precursor; PFAM: Glycosyl hydrolase, family 13, catalytic region; Alpha-amylase, C-terminal beta-sheet; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; Alpha-amylase, C-terminal beta-sheet; SPTR: Alpha amylase catalytic region. (437 aa)    
Predicted Functional Partners:
AEJ61063.1
PFAM: Carbohydrate phosphorylase; TIGRFAM: alpha-glucan phosphorylases; COGs: COG0058 Glucan phosphorylase; InterPro IPR011834:IPR000811; KEGG: sta:STHERM_c14440 hypothetical protein; PFAM: Glycosyl transferase, family 35; SPTR: Phosphorylase; TIGRFAM: Alpha-glucan phosphorylase.
  
 
 0.925
AEJ61827.1
PFAM: Glycosyl hydrolase family 65, C-terminal domain; Glycosyl hydrolase family 65 central catalytic domain; Glycosyl hydrolase family 65, N-terminal domain; COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196:IPR005195:IPR005194; KEGG: sta:STHERM_c15330 kojibiose phosphorylase; PFAM: Glycoside hydrolase family 65, central catalytic; Glycoside hydrolase family 65, N-terminal; Glycoside hydrolase, family 65, C-terminal; SPTR: Glycoside hydrolase family 65 central catalytic.
  
 
 0.910
AEJ61316.1
PFAM: Glycosyl hydrolases family 31; COGs: COG1501 Alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: sta:STHERM_c10190 alpha-glucosidase 2; PFAM: Glycoside hydrolase, family 31; SPTR: Alpha-glucosidase.
    
 0.905
AEJ61553.1
Glycoside hydrolase family 57; PFAM: Domain of unknown function (DUF1925); Glycosyl hydrolase family 57; Domain of unknown function (DUF1926); InterPro IPR004300:IPR015179; KEGG: sta:STHERM_c12500 alpha-amylase 1; PFAM: Glycoside hydrolase, family 57, core; Alpha-amylase/4-alpha-glucanotransferase, prokaryotic; SPTR: Glycoside hydrolase family 57.
    
 0.904
AEJ60999.1
PFAM: Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: sta:STHERM_c15010 oligo-1,6-glucosidase; PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha amylase catalytic region.
     
 
0.900
AEJ61966.1
PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase; COGs: COG0059 Ketol-acid reductoisomerase; InterPro IPR013116:IPR000506; KEGG: sta:STHERM_c16450 ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase C-terminal; Acetohydroxy acid isomeroreductase, catalytic; SPTR: Acetohydroxy acid isomeroreductase.
  
   
 0.623
AEJ61917.1
Glycoside hydrolase family 13 domain protein; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); InterPro IPR004193; KEGG: sta:STHERM_c15960 hypothetical protein; PFAM: Glycoside hydrolase, family 13, N-terminal; SPTR: Glycoside hydrolase family 13 domain protein.
  
  
 0.585
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
  
 0.571
AEJ61919.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: sta:STHERM_c15990 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer.
     
 0.529
AEJ62433.1
PFAM: Amino acid permease; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG0531 Amino acid transporter; InterPro IPR004841:IPR002178; KEGG: sta:STHERM_c21330 hypothetical protein; PFAM: Amino acid permease-associated region; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Amino acid permease-associated region.
    
 0.523
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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