STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61924.1PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: sta:STHERM_c16040 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; SPTR: 3-hydroxyisobutyrate dehydrogenase. (283 aa)    
Predicted Functional Partners:
AEJ61568.1
PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase.
     
 0.805
thrS
threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; COGs: COG0441 Threonyl-tRNA synthetase; InterPro IPR002320:IPR012947:IPR002314:IPR004154; KEGG: sta:STHERM_c16030 threonyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; Anticodon-binding; SPTR: Ser-tRNA(Thr) hydrolase; threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; Belong [...]
       0.522
AEJ61922.1
Peptidase M32 carboxypeptidase Taq metallopeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
  
    0.464
AEJ61921.1
KEGG: sta:STHERM_c16010 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.454
rtcB
Protein of unknown function UPF0027; PFAM: Uncharacterized protein family UPF0027; COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: sta:STHERM_c16050 hypothetical protein; PFAM: Uncharacterised protein family UPF0027; SPTR: Putative uncharacterized protein; Belongs to the RtcB family.
       0.439
AEJ61920.1
KEGG: sta:STHERM_c16000 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.433
AEJ61926.1
UPF0103/Mediator of ErbB2-driven cell motility-containing protein; PFAM: Memo-like protein; COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: sta:STHERM_c16070 dioxygenase; PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo), related; SPTR: Putative uncharacterized protein.
       0.428
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.