STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rtcBProtein of unknown function UPF0027; PFAM: Uncharacterized protein family UPF0027; COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: sta:STHERM_c16050 hypothetical protein; PFAM: Uncharacterised protein family UPF0027; SPTR: Putative uncharacterized protein; Belongs to the RtcB family. (477 aa)    
Predicted Functional Partners:
AEJ61926.1
UPF0103/Mediator of ErbB2-driven cell motility-containing protein; PFAM: Memo-like protein; COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: sta:STHERM_c16070 dioxygenase; PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo), related; SPTR: Putative uncharacterized protein.
 
     0.786
AEJ61927.1
KEGG: sta:STHERM_c16060 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.548
AEJ62381.1
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
   
 0.452
AEJ61924.1
PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: sta:STHERM_c16040 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; SPTR: 3-hydroxyisobutyrate dehydrogenase.
       0.439
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.