STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61926.1UPF0103/Mediator of ErbB2-driven cell motility-containing protein; PFAM: Memo-like protein; COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: sta:STHERM_c16070 dioxygenase; PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo), related; SPTR: Putative uncharacterized protein. (275 aa)    
Predicted Functional Partners:
AEJ60606.1
AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: sta:STHERM_c03350 hypothetical protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1.
 
    0.805
rtcB
Protein of unknown function UPF0027; PFAM: Uncharacterized protein family UPF0027; COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: sta:STHERM_c16050 hypothetical protein; PFAM: Uncharacterised protein family UPF0027; SPTR: Putative uncharacterized protein; Belongs to the RtcB family.
 
     0.786
AEJ61927.1
KEGG: sta:STHERM_c16060 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.568
AEJ62413.1
PFAM: Radical SAM superfamily; B12 binding domain; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: sta:STHERM_c21130 methyltransferase; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
  
     0.545
AEJ61472.1
PFAM: Radical SAM superfamily; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR006638; KEGG: sta:STHERM_c11670 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
 
     0.500
AEJ61471.1
KEGG: sta:STHERM_c11660 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.485
AEJ60635.1
KEGG: sta:STHERM_c03850 GTP-binding protein; SPTR: Putative uncharacterized protein.
  
     0.466
AEJ61924.1
PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: sta:STHERM_c16040 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; SPTR: 3-hydroxyisobutyrate dehydrogenase.
       0.428
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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