STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61929.1PFAM: ABC-type uncharacterized transport system; COGs: COG3225 ABC-type uncharacterized transport system involved in gliding motility auxiliary component; InterPro IPR019196; KEGG: sta:STHERM_c16090 hypothetical protein; PFAM: ABC-type uncharacterised transport system; SPTR: ABC-type uncharacterized transport system. (721 aa)    
Predicted Functional Partners:
AEJ61930.1
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c16100 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
  
 0.871
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
       0.795
AEJ61928.1
KEGG: sta:STHERM_c16080 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ61767.1
PFAM: ABC-2 type transporter; KEGG: sta:STHERM_c13710 ABC-type transport system, permease; SPTR: Putative uncharacterized protein.
 
  
 0.733
AEJ61940.1
Protein of unknown function DUF2061, membrane; PFAM: Predicted membrane protein (DUF2061); InterPro IPR018638; KEGG: sta:STHERM_c16200 hypothetical protein; PFAM: Protein of unknown function DUF2061, membrane; SPTR: Putative uncharacterized protein.
 
     0.680
AEJ61941.1
PFAM: SirA-like protein; Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117:IPR006067:IPR001455; KEGG: sta:STHERM_c16210 ferredoxin-nitrite reductase; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; SirA-like; SPTR: Ferredoxin--nitrite reductase.
 
     0.663
AEJ61934.1
uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...]
       0.617
hemL
PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; InterPro IPR005814; KEGG: sta:STHERM_c16120 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase.
       0.610
AEJ61933.1
PFAM: Delta-aminolevulinic acid dehydratase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: sta:STHERM_c16130 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
       0.610
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.610
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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