| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEJ61141.1 | AEJ61160.1 | Spith_0866 | Spith_0886 | Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A. | 0.903 |
| AEJ61141.1 | AEJ61937.1 | Spith_0866 | Spith_1677 | Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M. | Sulfate adenylyltransferase, large subunit; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Adenylylsulphate kinase; TIGRFAM: sulfate adenylyltransferase, large subunit; COGs: COG2895 GTPase - Sulfate adenylate transferase subunit 1; InterPro IPR011779:IPR000795:IPR004161; KEGG: sta:STHERM_c16170 sulfate adenylyltransferase large subunit; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Sulfate adenylyltransferase, large subunit; TIGRFAM: Sulphate adenylyltransferase, large subunit. | 0.918 |
| AEJ61141.1 | AEJ61938.1 | Spith_0866 | Spith_1678 | Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M. | PFAM: Phosphoadenosine phosphosulfate reductase family; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: sta:STHERM_c16180 phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulphate reductase; SPTR: Sulfate adenylyltransferase subunit 2. | 0.429 |
| AEJ61141.1 | AEJ61939.1 | Spith_0866 | Spith_1679 | Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M. | Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. | 0.429 |
| AEJ61141.1 | AEJ61940.1 | Spith_0866 | Spith_1680 | Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M. | Protein of unknown function DUF2061, membrane; PFAM: Predicted membrane protein (DUF2061); InterPro IPR018638; KEGG: sta:STHERM_c16200 hypothetical protein; PFAM: Protein of unknown function DUF2061, membrane; SPTR: Putative uncharacterized protein. | 0.540 |
| AEJ61141.1 | AEJ61941.1 | Spith_0866 | Spith_1681 | Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M. | PFAM: SirA-like protein; Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117:IPR006067:IPR001455; KEGG: sta:STHERM_c16210 ferredoxin-nitrite reductase; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; SirA-like; SPTR: Ferredoxin--nitrite reductase. | 0.970 |
| AEJ61141.1 | AEJ61942.1 | Spith_0866 | Spith_1682 | Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M. | PFAM: Mov34/MPN/PAD-1 family; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; InterPro IPR000555; KEGG: sta:STHERM_c16220 Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; SMART: Mov34/MPN/PAD-1; SPTR: Mov34/MPN/PAD-1 family protein. | 0.445 |
| AEJ61160.1 | AEJ61141.1 | Spith_0886 | Spith_0866 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A. | Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M. | 0.903 |
| AEJ61160.1 | AEJ61937.1 | Spith_0886 | Spith_1677 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A. | Sulfate adenylyltransferase, large subunit; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Adenylylsulphate kinase; TIGRFAM: sulfate adenylyltransferase, large subunit; COGs: COG2895 GTPase - Sulfate adenylate transferase subunit 1; InterPro IPR011779:IPR000795:IPR004161; KEGG: sta:STHERM_c16170 sulfate adenylyltransferase large subunit; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Sulfate adenylyltransferase, large subunit; TIGRFAM: Sulphate adenylyltransferase, large subunit. | 0.918 |
| AEJ61160.1 | AEJ61938.1 | Spith_0886 | Spith_1678 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A. | PFAM: Phosphoadenosine phosphosulfate reductase family; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: sta:STHERM_c16180 phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulphate reductase; SPTR: Sulfate adenylyltransferase subunit 2. | 0.429 |
| AEJ61160.1 | AEJ61939.1 | Spith_0886 | Spith_1679 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A. | Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. | 0.429 |
| AEJ61160.1 | AEJ61940.1 | Spith_0886 | Spith_1680 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A. | Protein of unknown function DUF2061, membrane; PFAM: Predicted membrane protein (DUF2061); InterPro IPR018638; KEGG: sta:STHERM_c16200 hypothetical protein; PFAM: Protein of unknown function DUF2061, membrane; SPTR: Putative uncharacterized protein. | 0.540 |
| AEJ61160.1 | AEJ61941.1 | Spith_0886 | Spith_1681 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A. | PFAM: SirA-like protein; Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117:IPR006067:IPR001455; KEGG: sta:STHERM_c16210 ferredoxin-nitrite reductase; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; SirA-like; SPTR: Ferredoxin--nitrite reductase. | 0.970 |
| AEJ61160.1 | AEJ61942.1 | Spith_0886 | Spith_1682 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A. | PFAM: Mov34/MPN/PAD-1 family; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; InterPro IPR000555; KEGG: sta:STHERM_c16220 Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; SMART: Mov34/MPN/PAD-1; SPTR: Mov34/MPN/PAD-1 family protein. | 0.445 |
| AEJ61934.1 | AEJ61936.1 | Spith_1674 | Spith_1676 | uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...] | Hypothetical protein; PFAM: FAD binding domain; TIGRFAM: siroheme synthase, N-terminal domain; COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); KEGG: sta:STHERM_c16160 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.997 |
| AEJ61934.1 | AEJ61937.1 | Spith_1674 | Spith_1677 | uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...] | Sulfate adenylyltransferase, large subunit; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Adenylylsulphate kinase; TIGRFAM: sulfate adenylyltransferase, large subunit; COGs: COG2895 GTPase - Sulfate adenylate transferase subunit 1; InterPro IPR011779:IPR000795:IPR004161; KEGG: sta:STHERM_c16170 sulfate adenylyltransferase large subunit; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Sulfate adenylyltransferase, large subunit; TIGRFAM: Sulphate adenylyltransferase, large subunit. | 0.973 |
| AEJ61934.1 | AEJ61938.1 | Spith_1674 | Spith_1678 | uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...] | PFAM: Phosphoadenosine phosphosulfate reductase family; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: sta:STHERM_c16180 phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulphate reductase; SPTR: Sulfate adenylyltransferase subunit 2. | 0.943 |
| AEJ61934.1 | AEJ61939.1 | Spith_1674 | Spith_1679 | uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...] | Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. | 0.953 |
| AEJ61934.1 | AEJ61940.1 | Spith_1674 | Spith_1680 | uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...] | Protein of unknown function DUF2061, membrane; PFAM: Predicted membrane protein (DUF2061); InterPro IPR018638; KEGG: sta:STHERM_c16200 hypothetical protein; PFAM: Protein of unknown function DUF2061, membrane; SPTR: Putative uncharacterized protein. | 0.959 |
| AEJ61934.1 | AEJ61941.1 | Spith_1674 | Spith_1681 | uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...] | PFAM: SirA-like protein; Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117:IPR006067:IPR001455; KEGG: sta:STHERM_c16210 ferredoxin-nitrite reductase; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; SirA-like; SPTR: Ferredoxin--nitrite reductase. | 0.989 |