STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61941.1PFAM: SirA-like protein; Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117:IPR006067:IPR001455; KEGG: sta:STHERM_c16210 ferredoxin-nitrite reductase; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; SirA-like; SPTR: Ferredoxin--nitrite reductase. (737 aa)    
Predicted Functional Partners:
AEJ61937.1
Sulfate adenylyltransferase, large subunit; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Adenylylsulphate kinase; TIGRFAM: sulfate adenylyltransferase, large subunit; COGs: COG2895 GTPase - Sulfate adenylate transferase subunit 1; InterPro IPR011779:IPR000795:IPR004161; KEGG: sta:STHERM_c16170 sulfate adenylyltransferase large subunit; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Sulfate adenylyltransferase, large subunit; TIGRFAM: Sulphate adenylyltransferase, large subunit.
 
  
 0.999
AEJ61939.1
Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite.
 
 0.999
AEJ61940.1
Protein of unknown function DUF2061, membrane; PFAM: Predicted membrane protein (DUF2061); InterPro IPR018638; KEGG: sta:STHERM_c16200 hypothetical protein; PFAM: Protein of unknown function DUF2061, membrane; SPTR: Putative uncharacterized protein.
 
  
 0.990
AEJ61934.1
uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...]
 
  
 0.989
AEJ61938.1
PFAM: Phosphoadenosine phosphosulfate reductase family; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: sta:STHERM_c16180 phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulphate reductase; SPTR: Sulfate adenylyltransferase subunit 2.
 
  
 0.988
AEJ61141.1
Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M.
  
 
 0.972
AEJ61160.1
Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A.
  
 
 0.972
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
 
 
 0.919
AEJ61942.1
PFAM: Mov34/MPN/PAD-1 family; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; InterPro IPR000555; KEGG: sta:STHERM_c16220 Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; SMART: Mov34/MPN/PAD-1; SPTR: Mov34/MPN/PAD-1 family protein.
 
 
   0.915
AEJ61947.1
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR010035:IPR003749; KEGG: sta:STHERM_c16270 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis.
 
 
 
 0.907
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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