STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61948.1PFAM: ROK family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sta:STHERM_c16280 transcriptional repressor; PFAM: ROK; SPTR: ROK family protein. (384 aa)    
Predicted Functional Partners:
xylA
PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase; COGs: COG2115 Xylose isomerase; HAMAP: Xylose isomerase; InterPro IPR013452:IPR012307:IPR001998; KEGG: sta:STHERM_c16290 xylose isomerase; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase; TIGRFAM: Xylose isomerase, bacterial type; Belongs to the xylose isomerase family.
     
 0.560
AEJ61937.1
Sulfate adenylyltransferase, large subunit; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Adenylylsulphate kinase; TIGRFAM: sulfate adenylyltransferase, large subunit; COGs: COG2895 GTPase - Sulfate adenylate transferase subunit 1; InterPro IPR011779:IPR000795:IPR004161; KEGG: sta:STHERM_c16170 sulfate adenylyltransferase large subunit; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Sulfate adenylyltransferase, large subunit; TIGRFAM: Sulphate adenylyltransferase, large subunit.
     
 0.463
AEJ61941.1
PFAM: SirA-like protein; Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117:IPR006067:IPR001455; KEGG: sta:STHERM_c16210 ferredoxin-nitrite reductase; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; SirA-like; SPTR: Ferredoxin--nitrite reductase.
  
  
 0.427
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
 
     0.422
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.419
AEJ61940.1
Protein of unknown function DUF2061, membrane; PFAM: Predicted membrane protein (DUF2061); InterPro IPR018638; KEGG: sta:STHERM_c16200 hypothetical protein; PFAM: Protein of unknown function DUF2061, membrane; SPTR: Putative uncharacterized protein.
       0.408
AEJ61942.1
PFAM: Mov34/MPN/PAD-1 family; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; InterPro IPR000555; KEGG: sta:STHERM_c16220 Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; SMART: Mov34/MPN/PAD-1; SPTR: Mov34/MPN/PAD-1 family protein.
       0.406
AEJ61943.1
PFAM: SirA-like protein; InterPro IPR001455; KEGG: sta:STHERM_c16230 hypothetical protein; PFAM: SirA-like; SPTR: SirA-like domain-containing protein; Belongs to the sulfur carrier protein TusA family.
       0.406
AEJ61938.1
PFAM: Phosphoadenosine phosphosulfate reductase family; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: sta:STHERM_c16180 phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulphate reductase; SPTR: Sulfate adenylyltransferase subunit 2.
       0.400
AEJ61939.1
Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite.
       0.400
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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