STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xylAPFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase; COGs: COG2115 Xylose isomerase; HAMAP: Xylose isomerase; InterPro IPR013452:IPR012307:IPR001998; KEGG: sta:STHERM_c16290 xylose isomerase; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase; TIGRFAM: Xylose isomerase, bacterial type; Belongs to the xylose isomerase family. (440 aa)    
Predicted Functional Partners:
AEJ61100.1
PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: sta:STHERM_c13310 xylulokinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; SPTR: Carbohydrate kinase, FGGY.
 
 
 0.960
AEJ60410.1
PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: sta:STHERM_c01350 xylulose kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; SPTR: Carbohydrate kinase, FGGY.
 
 
 0.952
AEJ60705.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: ace:Acel_2120 ribokinase-like domain-containing protein; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
    
 0.911
AEJ60759.1
PFAM: ROK family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sta:STHERM_c18040 hypothetical protein; PFAM: ROK; SPTR: Fructokinase.
    
 0.910
AEJ62193.1
PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006102:IPR006103; KEGG: sta:STHERM_c18890 carbohydrate binding family 6; PFAM: Glycoside hydrolase family 2, carbohydrate-binding; Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich; Glycoside hydrolase family 2, TIM barrel; SPTR: Glycoside hydrolase family 2 sugar binding.
    
 0.811
AEJ60931.1
PFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; COGs: COG0837 Glucokinase; InterPro IPR003836; KEGG: sta:STHERM_c06370 glucokinase; PFAM: Glucokinase; SPTR: Glucokinase.
     
 0.808
AEJ61948.1
PFAM: ROK family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sta:STHERM_c16280 transcriptional repressor; PFAM: ROK; SPTR: ROK family protein.
     
 0.560
fabV
Reductase; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA); Belongs to the TER reductase family.
       0.520
AEJ60593.1
Transporter; PFAM: family; TIGRFAM: D-xylose ABC transporter, substrate-binding protein; COGs: COG4213 ABC-type xylose transport system periplasmic component; KEGG: sta:STHERM_c03240 transporter; SPTR: D-xylose ABC transporter (Substrate-binding protein).
 
  
 0.509
AEJ62151.1
PFAM: Glycosyl hydrolases family 43; COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: sta:STHERM_c18500 beta-xylosidase; PFAM: Glycoside hydrolase, family 43; SPTR: Xylan 1,4-beta-xylosidase.
 
  
 0.503
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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