Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61956.1PFAM: Aldo/keto reductase family; COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: sta:STHERM_c16360 hypothetical protein; PFAM: Aldo/keto reductase; SPTR: Aldo/keto reductase. (323 aa)    
Predicted Functional Partners:
AEJ61957.1
Hypothetical protein; PFAM: Prolyl oligopeptidase family; KEGG: srm:SRM_01848 conserved hypothetical protein, secreted; SPTR: Putative uncharacterized protein.
       0.650
AEJ61954.1
Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain; GGDEF domain; COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633; KEGG: sta:STHERM_c16340 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase/phosphodiesterase.
       0.534
AEJ61955.1
Methyl-accepting chemotaxis sensory transducer; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Putative Fe-S cluster; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR001450:IPR007202; KEGG: sta:STHERM_c16350 transcriptional regulator containing a ferredoxin domain; PFAM: Chemotaxis methyl-accepting receptor, signalling; Putative Fe-S cluster; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis senso [...]
       0.534
AEJ60761.1
PFAM: Histone deacetylase domain; COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: sta:STHERM_c18020 histone deacetylase superfamily; PFAM: Histone deacetylase superfamily; SPTR: Histone deacetylase superfamily.
   
  0.455
AEJ61247.1
PFAM: Ankyrin repeat; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: sta:STHERM_c09480 ankyrin repeat-containing protein; PFAM: Ankyrin repeat; SMART: Ankyrin repeat; SPTR: Ankyrin.
  
 
 0.433
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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