STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61960.1Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; PFAM: D-alanyl-D-alanine carboxypeptidase; COGs: COG1876 D-alanyl-D-alanine carboxypeptidase; InterPro IPR003709; KEGG: sta:STHERM_c16390 hypothetical protein; PFAM: Peptidase M15B/M15C, D,D-carboxypeptidase VanY/endolysins; SPTR: Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin. (275 aa)    
Predicted Functional Partners:
AEJ62110.1
PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967:IPR012907; KEGG: sta:STHERM_c17820 D-alanyl-D-alanine carboxypeptidase A; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; SPTR: Serine-type D-Ala-D-Ala carboxypeptidase.
     
 0.915
AEJ61705.1
Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR011816; KEGG: sta:STHERM_c07150 penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A.
  
  
  0.912
lon-2
Anti-sigma H sporulation factor, LonB; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.810
recO
DNA repair protein recO; Involved in DNA repair and RecF pathway recombination.
       0.600
AEJ61961.1
KEGG: sta:STHERM_c16400 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.581
AEJ61962.1
PFAM: Peptidase family U32; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: sta:STHERM_c16410 hypothetical protein; PFAM: Peptidase U32; SPTR: Peptidase U32.
       0.568
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
   
 0.474
AEJ62509.1
PFAM: Bacterial capsule synthesis protein PGA_cap; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: sta:STHERM_c22100 hypothetical protein; PFAM: Capsule synthesis protein, CapA; SPTR: Capsule synthesis protein, CapA.
     0.436
AEJ62523.1
PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD); COGs: COG0813 Purine-nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase deoD-type; InterPro IPR004402:IPR000845; KEGG: sta:STHERM_c22230 purine nucleoside phosphorylase DeoD-type; PFAM: Nucleoside phosphorylase; SPTR: Purine-nucleoside phosphorylase; TIGRFAM: Purine nucleoside phosphorylase.
  
    0.436
AEJ61535.1
PFAM: Bacterial capsule synthesis protein PGA_cap; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: sta:STHERM_c12320 hypothetical protein; PFAM: Capsule synthesis protein, CapA; SPTR: Capsule synthesis protein, CapA.
     0.408
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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