STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61962.1PFAM: Peptidase family U32; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: sta:STHERM_c16410 hypothetical protein; PFAM: Peptidase U32; SPTR: Peptidase U32. (414 aa)    
Predicted Functional Partners:
AEJ61961.1
KEGG: sta:STHERM_c16400 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.636
lon-2
Anti-sigma H sporulation factor, LonB; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
   
 
 0.600
AEJ61960.1
Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; PFAM: D-alanyl-D-alanine carboxypeptidase; COGs: COG1876 D-alanyl-D-alanine carboxypeptidase; InterPro IPR003709; KEGG: sta:STHERM_c16390 hypothetical protein; PFAM: Peptidase M15B/M15C, D,D-carboxypeptidase VanY/endolysins; SPTR: Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin.
       0.568
AEJ61504.1
TGS domain-containing protein; PFAM: Phosphoribulokinase / Uridine kinase family; COGs: COG0572 Uridine kinase; InterPro IPR003593:IPR004095; KEGG: sta:STHERM_c11970 hypothetical protein; PFAM: TGS; SMART: ATPase, AAA+ type, core; SPTR: TGS domain-containing protein.
  
    0.518
recO
DNA repair protein recO; Involved in DNA repair and RecF pathway recombination.
       0.436
AEJ60471.1
Conserved hypothetical protein CHP01212; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, TIGR01212 family; COGs: COG1242 Fe-S oxidoreductase; InterPro IPR007197:IPR006638:IPR005911; KEGG: sta:STHERM_c02000 radical SAM protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01212.
 
    0.425
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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