Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61963.1PFAM: Domain of unknown function (DUF303); Glycosyl hydrolases family 2, sugar binding domain; InterPro IPR005181:IPR006104; KEGG: sta:STHERM_c16420 sialic acid-specific 9-O-acetylesterase; PFAM: Protein of unknown function DUF303, acetylesterase putative; Glycoside hydrolase family 2, carbohydrate-binding; SPTR: Putative uncharacterized protein. (622 aa)    
Predicted Functional Partners:
AEJ61964.1
PFAM: Glycosyl hydrolase family 9; Carbohydrate binding domain; N-terminal ig-like domain of cellulase; InterPro IPR003305:IPR004197:IPR001701; KEGG: sta:STHERM_c16430 cellodextrinase; PFAM: Glycoside hydrolase, family 9; Carbohydrate-binding, CenC-like; Glycoside hydrolase, family 9, N-terminal, Ig-like; SPTR: Glycoside hydrolase family 9.
 
 
 0.829
AEJ60369.1
N-acylglucosamine 2-epimerase; Catalyzes the reversible epimerization of cellobiose to 4-O- beta-D-glucopyranosyl-D-mannose (Glc-Man).
 
     0.731
AEJ61584.1
PFAM: Glycosyl hydrolase family 10; COGs: COG3693 Beta-1 4-xylanase; InterPro IPR001000; KEGG: sta:STHERM_c08530 beta-1,4-xylanase; PFAM: Glycoside hydrolase, family 10; SMART: Glycoside hydrolase, family 10; SPTR: Endo-1,4-beta-xylanase.
 
 
 
 0.680
AEJ61028.1
PFAM: Glycosyl hydrolases family 43; InterPro IPR006710; KEGG: sta:STHERM_c14740 hypothetical protein; PFAM: Glycoside hydrolase, family 43; SPTR: Alpha-N-arabinofuranosidase.
 
   
 0.672
AEJ60681.1
PFAM: Glycosyl hydrolases family 28; COGs: COG5434 Endopygalactorunase; InterPro IPR006626:IPR000743; KEGG: sta:STHERM_c04310 hypothetical protein; PFAM: Glycoside hydrolase, family 28; SPTR: Glycoside hydrolase family 28.
 
 
 0.649
AEJ62098.1
PFAM: Glycosyl hydrolase family 10; COGs: COG3693 Beta-1 4-xylanase; InterPro IPR001000; KEGG: sta:STHERM_c17680 xylanase; PFAM: Glycoside hydrolase, family 10; SMART: Glycoside hydrolase, family 10; SPTR: Glycoside hydrolase family 10.
 
 
 
 0.629
AEJ61794.1
PFAM: Glycosyl hydrolase family 67 C-terminus; Glycosyl hydrolase family 67 middle domain; Glycosyl hydrolase family 67 N-terminus; COGs: COG3661 Alpha-glucuronidase; InterPro IPR005154:IPR011100:IPR011099; KEGG: sta:STHERM_c13950 hypothetical protein; PFAM: Glycosyl hydrolase 67 middle; Glycoside hydrolase family 67; Glycosyl hydrolase 67, C-terminal; SPTR: Alpha-glucuronidase.
 
     0.607
AEJ60368.1
Glycosidase related protein; Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose; Belongs to the glycosyl hydrolase 130 family.
  
   
 0.602
AEJ60410.1
PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: sta:STHERM_c01350 xylulose kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; SPTR: Carbohydrate kinase, FGGY.
 
     0.599
AEJ60370.1
Hemagluttinin repeat-containing protein; InterPro IPR008619; KEGG: sta:STHERM_c00960 hypothetical protein; PFAM: Filamentous haemagglutinin, bacterial; SPTR: Hemagluttinin repeat-containing protein.
  
 
 0.576
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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