STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61968.1KEGG: sta:STHERM_c16470 lactoylglutathione lyase-like lyase; SPTR: Methylmalonyl-CoA epimerase. (148 aa)    
Predicted Functional Partners:
AEJ61969.1
KEGG: sta:STHERM_c16480 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ60857.1
PFAM: Xylose isomerase-like TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sta:STHERM_c05570 xylose isomerase domain-containing protein; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase domain-containing protein TIM barrel.
 
   
 0.595
AEJ61580.1
PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482:IPR004549; KEGG: sta:STHERM_c08570 pyruvate carboxylase subunit A; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; SPTR: Biotin carboxylase; acetyl-CoA carboxylase [...]
  
  
 0.532
AEJ61972.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 008207:IPR013767:IPR013656; KEGG: sta:STHERM_c16510 autoinducer 2 sensor kinase/phosphatase LuxQ; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; PAS fold; Signal transduction response regulator, receiver region [...]
     
 0.512
AEJ61971.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c16500 transcriptional regulatory protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
     
 0.511
AEJ61970.1
Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.497
AEJ62097.1
PFAM: GtrA-like protein; COGs: COG2246 membrane protein; InterPro IPR007267; KEGG: sta:STHERM_c17670 membrane spanning protein; PFAM: GtrA-like protein; SPTR: GtrA family protein.
  
     0.476
AEJ61243.1
PFAM: Fumarylacetoacetate (FAA) hydrolase family; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: sta:STHERM_c09440 fumarylacetoacetate hydrolase domain-containing protein 2A; PFAM: Fumarylacetoacetase, C-terminal-like; SPTR: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase.
  
  
 0.457
AEJ61710.1
PFAM: Cellulase (glycosyl hydrolase family 5); COGs: COG2730 Endoglucanase; InterPro IPR001547; KEGG: sta:STHERM_c07100 endoglucanase; PFAM: Glycoside hydrolase, family 5; SPTR: Glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.408
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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