Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62006.1PFAM: Glycosyl Hydrolase Family 88; InterPro IPR010905; KEGG: sma:SAV_44 unsaturated glucuronyl hydrolase; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88. (379 aa)    
Predicted Functional Partners:
AEJ62005.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ttr:Tter_2523 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.
       0.771
AEJ62007.1
PFAM: Heparinase II/III-like protein; KEGG: sco:SCO3500 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.756
AEJ62004.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ttr:Tter_2216 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family.
       0.730
AEJ62008.1
PFAM: Heparinase II/III-like protein; InterPro IPR012480; KEGG: gym:GYMC10_3686 heparinase II/III family protein; PFAM: Heparinase II/III-like; SPTR: Heparinase II/III family protein.
       0.718
AEJ62009.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: rmr:Rmar_1167 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR.
       0.718
AEJ60661.1
PFAM: Glycosyl Hydrolase Family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: sta:STHERM_c04120 unsaturated glucuronyl hydrolase; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88.
  
     0.713
AEJ62010.1
PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sco:SCO3506 LacI family transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family.
       0.682
kduI
4-deoxy-L-threo-5-hexosulose-uronateketol- isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
     0.673
AEJ61616.1
PFAM: Glycosyl Hydrolase Family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: sta:STHERM_c08190 glycosyl hydrolase, family 88; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88.
  
     0.672
AEJ60667.1
KEGG: sta:STHERM_c04180 alpha-L-fucosidase 2 precursor; SPTR: Alpha-L-fucosidase.
  
 
   0.609
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.