STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62019.1PFAM: Diacylglycerol kinase catalytic domain; COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: sta:STHERM_c16860 hypothetical protein; PFAM: Diacylglycerol kinase, catalytic region; SPTR: Diacylglycerol kinase catalytic region. (346 aa)    
Predicted Functional Partners:
AEJ62020.1
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c16870 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
       0.546
AEJ62021.1
PFAM: ABC-2 type transporter; COGs: COG1668 ABC-type Na+ efflux pump permease component; InterPro IPR013525; KEGG: sta:STHERM_c16880 ABC-2 type transporter family; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
       0.546
bpt
arginyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.
       0.546
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
  0.430
AEJ61917.1
Glycoside hydrolase family 13 domain protein; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); InterPro IPR004193; KEGG: sta:STHERM_c15960 hypothetical protein; PFAM: Glycoside hydrolase, family 13, N-terminal; SPTR: Glycoside hydrolase family 13 domain protein.
 
   
 0.419
AEJ61321.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit.
     
 0.408
AEJ62023.1
Protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932:IPR010822; KEGG: ssm:Spirs_1299 protein serine/threonine phosphatase; PFAM: Sporulation stage II, protein E C-terminal; SMART: Protein phosphatase 2C-related; SPTR: Protein serine/threonine phosphatase.
       0.406
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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