STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutS2MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (806 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 
0.941
AEJ60608.1
PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA); COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: sta:STHERM_c03370 fibronectin-binding protein; PFAM: Protein of unknown function DUF814; Fibronectin-binding A, N-terminal; SPTR: Putative uncharacterized protein.
 
     0.729
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.727
AEJ62028.1
KEGG: sta:STHERM_c16970 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.672
AEJ62030.1
KEGG: sta:STHERM_c16990 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.671
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
  
 
   0.651
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
   0.650
AEJ62029.1
KEGG: sta:STHERM_c16980 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.640
rpsU
PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; HAMAP: Ribosomal protein S21; InterPro IPR001911; KEGG: sta:STHERM_c06550 30S ribosomal protein S21; PFAM: Ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
   
   0.636
rpmI
PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; HAMAP: Ribosomal protein L35; InterPro IPR001706; KEGG: sta:STHERM_c07800 50S ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
   
   0.636
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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