Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62037.1Pentapeptide repeat protein; COGs: COG1357 Uncharacterized low-complexity protein; InterPro IPR001646; KEGG: sta:STHERM_c17050 pentapeptide protein; PFAM: Pentapeptide repeat; SPTR: Pentapeptide repeat protein. (202 aa)    
Predicted Functional Partners:
AEJ62038.1
PFAM: Metallo-beta-lactamase superfamily; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: sta:STHERM_c17070 beta lactamase like protein; SPTR: Putative uncharacterized protein.
     
 0.810
AEJ62036.1
KEGG: sta:STHERM_c17060 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
 
     0.684
rsgA-2
Sigma 54 interacting domain protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
    0.626
AEJ61188.1
KEGG: sta:STHERM_c08890 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.597
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.593
AEJ61626.1
Protein of unknown function YGGT; PFAM: YGGT family; InterPro IPR003425; KEGG: sta:STHERM_c08080 hypothetical protein; PFAM: Protein of unknown function YGGT; SPTR: Putative uncharacterized protein.
 
     0.553
AEJ60544.1
PFAM: Uncharacterised protein family (UPF0158); KEGG: sta:STHERM_c02740 hypothetical protein; SPTR: Putative uncharacterized protein.
  
   
 0.531
AEJ61757.1
PFAM: Protein of unknown function (DUF2807); KEGG: sta:STHERM_c13580 hypothetical protein; SPTR: Putative uncharacterized protein.
   
   0.525
AEJ62146.1
Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain; LysM domain; InterPro IPR008258:IPR018392:IPR002482; KEGG: sta:STHERM_c18450 transglycosylase, SLT family; PFAM: Lytic transglycosylase-like, catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Lytic transglycosylase catalytic.
   
 
 0.493
AEJ62522.1
Glycoside hydrolase family 37; PFAM: Trehalase; COGs: COG1626 Neutral trehalase; InterPro IPR001661; KEGG: sta:STHERM_c22220 hypothetical protein; PFAM: Glycoside hydrolase, family 37; SPTR: Glycoside hydrolase family 37.
  
     0.493
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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