STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62045.1PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sta:STHERM_c17140 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (357 aa)    
Predicted Functional Partners:
AEJ61123.1
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.953
AEJ62289.1
PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sta:STHERM_c19820 heptaprenyl diphosphate synthase component II; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.922
AEJ62044.1
PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); COGs: COG0761 Penicillin tolerance protein; InterPro IPR003451; KEGG: sta:STHERM_c17130 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PFAM: LytB protein; SPTR: Hydroxymethylbutenyl pyrophosphate reductase; TIGRFAM: LytB protein.
  
 
 0.918
AEJ60941.1
PFAM: Heptaprenyl diphosphate synthase component I; COGs: COG4769 membrane protein; InterPro IPR010898; KEGG: sta:STHERM_c06470 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: Heptaprenyl diphosphate synthase component I.
  
 
 0.916
AEJ62046.1
PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: sta:STHERM_c17150 FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase.
  
    0.598
AEJ62099.1
Hypothetical protein; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); KEGG: sta:STHERM_c17700 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.580
xseB
Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
  
 0.514
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
    0.461
AEJ62063.1
PFAM: Nucleoside diphosphate kinase; COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: sta:STHERM_c17330 nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase, core; SMART: Nucleoside diphosphate kinase, core; SPTR: Nucleoside diphosphate kinase; Belongs to the NDK family.
  
 
 0.455
AEJ60686.1
PFAM: Tetratricopeptide repeat; Protein of unknown function (DUF1570); InterPro IPR019734:IPR013105:IPR001440; KEGG: sta:STHERM_c04360 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
     0.446
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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