Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62045.1PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sta:STHERM_c17140 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (357 aa)    
Predicted Functional Partners:
AEJ61123.1
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.954
AEJ62044.1
PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); COGs: COG0761 Penicillin tolerance protein; InterPro IPR003451; KEGG: sta:STHERM_c17130 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PFAM: LytB protein; SPTR: Hydroxymethylbutenyl pyrophosphate reductase; TIGRFAM: LytB protein.
  
 
 0.918
AEJ62046.1
PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: sta:STHERM_c17150 FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase.
  
    0.602
AEJ62099.1
Hypothetical protein; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); KEGG: sta:STHERM_c17700 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.595
AEJ60893.1
D-alanine--D-alanine ligase domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
 
 0.509
xseB
Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
  
 0.491
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
    0.450
AEJ62169.1
KEGG: sta:STHERM_c18670 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.445
AEJ60686.1
PFAM: Tetratricopeptide repeat; Protein of unknown function (DUF1570); InterPro IPR019734:IPR013105:IPR001440; KEGG: sta:STHERM_c04360 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
     0.444
AEJ61297.1
PFAM: Lyase; Adenylosuccinate lyase C-terminus; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362; KEGG: sta:STHERM_c10000 adenylosuccinate lyase; PFAM: Fumarate lyase; SPTR: Fumarate lyase.
 
  
 0.443
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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