STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62047.1PFAM: Protein of unknown function (DUF401); TIGRFAM: converved hypothetical integral membrane protein; COGs: COG1906 conserved hypothetical protein; InterPro IPR007294; KEGG: sta:STHERM_c17160 membrane spanning protein; PFAM: Protein of unknown function DUF401; SPTR: Putative uncharacterized protein. (431 aa)    
Predicted Functional Partners:
AEJ62048.1
Acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846:IPR012001:IPR012000:IPR011766; KEGG: sta:STHERM_c17170 acetolactate synthase large subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine p [...]
  
    0.553
AEJ62049.1
PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR004789:IPR002912:IPR019455; KEGG: sta:STHERM_c17180 acetolate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit.
       0.552
AEJ61981.1
KEGG: sta:STHERM_c16620 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.548
AEJ61002.1
Protein of unknown function DUF2078, membrane; PFAM: Predicted membrane protein (DUF2078); InterPro IPR018649; KEGG: sta:STHERM_c14980 hypothetical protein; PFAM: Protein of unknown function DUF2078, membrane; SPTR: Putative uncharacterized protein.
  
     0.491
AEJ62413.1
PFAM: Radical SAM superfamily; B12 binding domain; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: sta:STHERM_c21130 methyltransferase; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
  
     0.485
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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