Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62064.1Glycosidase related protein; PFAM: Domain of unknown function (DUF377); COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: sta:STHERM_c17340 glycosidase; PFAM: Glycosidase, PH1107-related; SPTR: Glycosidase related protein. (487 aa)    
Predicted Functional Partners:
AEJ62065.1
PFAM: Glycosyl transferases group 1; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sta:STHERM_c17350 glycosyltransferase; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1.
 
     0.906
AEJ62066.1
Glycosidase related protein; PFAM: Domain of unknown function (DUF377); COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: sta:STHERM_c17360 glycosidase; PFAM: Glycosidase, PH1107-related; SPTR: Glycosidase related protein.
 
    
0.700
AEJ62063.1
PFAM: Nucleoside diphosphate kinase; COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: sta:STHERM_c17330 nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase, core; SMART: Nucleoside diphosphate kinase, core; SPTR: Nucleoside diphosphate kinase; Belongs to the NDK family.
       0.539
AEJ62062.1
Amino-acid N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; Amino acid kinase family; TIGRFAM: amino-acid N-acetyltransferase; COGs: COG0548 Acetylglutamate kinase; InterPro IPR010167:IPR001048:IPR000182; KEGG: sta:STHERM_c17320 amino acid acetyltransferase; PFAM: GCN5-related N-acetyltransferase; Aspartate/glutamate/uridylate kinase; SPTR: Amino-acid N-acetyltransferase; TIGRFAM: Amino-acid N-acetyltransferase (ArgA); Belongs to the acetyltransferase family.
       0.493
AEJ60369.1
N-acylglucosamine 2-epimerase; Catalyzes the reversible epimerization of cellobiose to 4-O- beta-D-glucopyranosyl-D-mannose (Glc-Man).
 
   
 0.446
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]