STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62071.1Protein of unknown function DUF2166; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG4696 conserved hypothetical protein; InterPro IPR019229; KEGG: sta:STHERM_c17410 hypothetical protein; PFAM: Protein of unknown function DUF2166; SPTR: Putative uncharacterized protein. (148 aa)    
Predicted Functional Partners:
AEJ62070.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: sta:STHERM_c17400 short chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR.
       0.732
AEJ62244.1
RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
   
    0.590
AEJ62072.1
Protein of unknown function DUF125 transmembrane; PFAM: VIT family; COGs: COG1814 Uncharacterized membrane protein; InterPro IPR008217; KEGG: sta:STHERM_c17420 hypothetical protein; PFAM: Protein of unknown function DUF125, transmembrane; SPTR: Putative uncharacterized protein.
       0.584
AEJ61940.1
Protein of unknown function DUF2061, membrane; PFAM: Predicted membrane protein (DUF2061); InterPro IPR018638; KEGG: sta:STHERM_c16200 hypothetical protein; PFAM: Protein of unknown function DUF2061, membrane; SPTR: Putative uncharacterized protein.
  
     0.522
trmH
tRNA/rRNA methyltransferase (SpoU); Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
     0.413
AEJ62069.1
Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: sta:STHERM_c17390 heat shock protein; PFAM: Heat shock protein Hsp20; SPTR: Putative heat shock protein.
       0.412
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.