STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62077.1UPF0178 protein yaiI; PFAM: Uncharacterized BCR, YaiI/YqxD family COG1671; COGs: COG1671 conserved hypothetical protein; HAMAP: Protein of unknown function DUF188; InterPro IPR003791; KEGG: sta:STHERM_c17470 hypothetical protein; PFAM: Protein of unknown function DUF188; SPTR: UPF0178 protein SpithDRAFT_1414; Belongs to the UPF0178 family. (154 aa)    
Predicted Functional Partners:
AEJ62078.1
PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: sta:STHERM_c17490 mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type I; SPTR: Mannose-6-phosphate isomerase, class I; TIGRFAM: Mannose-6-phosphate isomerase, type I.
       0.811
pfp-2
Diphosphate/fructose-6-phosphate1- phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
       0.527
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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