Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62088.1PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: sta:STHERM_c17580 nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase. (169 aa)    
Predicted Functional Partners:
AEJ61881.1
PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: shg:Sph21_2015 nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase.
  
     0.695
AEJ62089.1
KEGG: sta:STHERM_c17590 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.555
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.538
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.532
AEJ62091.1
Auxin Efflux Carrier; PFAM: Membrane transport protein; COGs: COG0679 permease; InterPro IPR004776; KEGG: sta:STHERM_c17610 hypothetical protein; PFAM: Auxin efflux carrier; SPTR: Auxin Efflux Carrier.
       0.468
AEJ61155.1
Abortive infection protein; PFAM: CAAX amino terminal protease family; InterPro IPR003675; KEGG: sta:STHERM_c12770 hypothetical protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein.
  
  
 0.460
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
  
  
 0.457
AEJ62264.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19580 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
  
 0.442
AEJ62265.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19590 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
  
 0.442
AEJ62332.1
PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family; InterPro IPR013525; KEGG: sta:STHERM_c20340 ABC-type Nod factor export system, permease; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
  
 0.442
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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