Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62108.1KEGG: sta:STHERM_c17800 tetratricopeptide TPR2; SPTR: Putative uncharacterized protein. (168 aa)    
Predicted Functional Partners:
AEJ62109.1
Hypothetical protein; PFAM: NmrA-like family; COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR008030; KEGG: sta:STHERM_c17810 hypothetical protein; SPTR: NmrA family protein.
   
 
 0.548
AEJ62106.1
GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: sta:STHERM_c17770 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase.
  
    0.516
AEJ62107.1
Hypothetical protein; PFAM: Metallo-beta-lactamase superfamily; KEGG: sta:STHERM_c17780 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.513
htpG
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
   
 0.501
AEJ61119.1
WD40 repeat-containing protein; PFAM: WD domain, G-beta repeat; InterPro IPR019781:IPR001680; KEGG: sta:STHERM_c13130 hypothetical protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat; SPTR: WD40 repeat, subgroup.
    
 0.485
AEJ61247.1
PFAM: Ankyrin repeat; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: sta:STHERM_c09480 ankyrin repeat-containing protein; PFAM: Ankyrin repeat; SMART: Ankyrin repeat; SPTR: Ankyrin.
   
 0.479
AEJ61005.1
PFAM: Cytochrome b5-like Heme/Steroid binding domain; InterPro IPR001199; KEGG: sta:STHERM_c14910 soluble cytochrome b558; PFAM: Cytochrome b5; SPTR: Cytochrome b5.
    
 0.474
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.464
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
    0.457
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.449
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (16%) [HD]