Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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[Homology]
Score
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (266 aa)    
Predicted Functional Partners:
AEJ61123.1
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 0.934
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
    
 0.934
AEJ62117.1
PFAM: Transglycosylase SLT domain; COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: sta:STHERM_c17880 transglycosylase, SLT family; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic transglycosylase catalytic.
  
  
 0.828
AEJ62118.1
KEGG: sta:STHERM_c17890 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.781
AEJ62115.1
Cell division FtsK/SpoIIIE; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543:IPR018541:IPR003593; KEGG: sta:STHERM_c17860 DNA translocase FtsK; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: ATPase, AAA+ type, core; SPTR: Cell division protein FtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family.
     
 0.618
AEJ62114.1
KEGG: sta:STHERM_c17850 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.477
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.465
AEJ62119.1
Integrase catalytic region; PFAM: Integrase core domain; InterPro IPR001584; KEGG: tde:TDE2472 ISTde1, transposase; PFAM: Integrase, catalytic core; SPTR: Integrase catalytic region.
       0.459
AEJ61321.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit.
       0.426
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
  
 0.412
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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