STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62120.1Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: sta:STHERM_c18210 transcriptional regulatory protein; PFAM: Cyclic nucleotide-binding; SMART: Cyclic nucleotide-binding; SPTR: Putative transcriptional regulator, Crp/Fnr family. (412 aa)    
Predicted Functional Partners:
AEJ61394.1
Adenylate/guanylate cyclase with Chase sensor; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR007890:IPR001054; KEGG: sta:STHERM_c10940 hypothetical protein; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase with Chase sensor.
 
 
 
 0.816
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
  
 
   0.783
AEJ60381.1
Adenylate/guanylate cyclase with TPR repeats; PFAM: Adenylate and Guanylate cyclase catalytic domain; HAMP domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR003660:IPR001054:IPR013105; KEGG: sta:STHERM_c01070 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; Tetratricopeptide TPR2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SPTR: Adenylate/guanylate cyclase with integral membrane sensor.
 
 
 0.757
AEJ61258.1
PFAM: Radical SAM superfamily; InterPro IPR007197; KEGG: sta:STHERM_c09600 hypothetical protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein.
  
  
 0.756
AEJ62134.1
Protein of unknown function DUF2225; PFAM: Uncharacterized protein conserved in bacteria (DUF2225); COGs: COG1655 conserved hypothetical protein; InterPro IPR018708; KEGG: sta:STHERM_c18340 hypothetical protein; PFAM: Protein of unknown function DUF2225; SPTR: Putative uncharacterized protein.
  
     0.754
AEJ61022.1
KEGG: sta:STHERM_c14800 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.741
AEJ62073.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; 7TM diverse intracellular signalling; 7TMR-DISM extracellular 2; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: sta:STHERM_c17430 adenylate cyclase / guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase; manually curated.
 
 
 
 0.729
AEJ61221.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
   
 0.727
AEJ61214.1
KEGG: sta:STHERM_c09150 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.716
AEJ61708.1
P83100 family protein; PFAM: Borrelia P83/100 protein; InterPro IPR007926; KEGG: sta:STHERM_c07120 antigen; PFAM: Borrelia P83100; SPTR: P83100 family protein.
  
     0.713
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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