STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysSPFAM: tRNA synthetases class I (C) catalytic domain; TIGRFAM: cysteinyl-tRNA synthetase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR002308; KEGG: sta:STHERM_c18260 hypothetical protein; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (470 aa)    
Predicted Functional Partners:
AEJ60514.1
Serine acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: sta:STHERM_c02440 serine acetyltransferase; SPTR: Serine O-acetyltransferase.
 
  
 0.948
AEJ61160.1
Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12700 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A.
  
 
 0.904
AEJ61141.1
Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: sta:STHERM_c12900 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M.
  
 
 0.822
AEJ62124.1
RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: sta:STHERM_c18250 hypothetical protein; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70.
  
  
 0.735
serS
Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
 
 0.727
leuS
PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR015945:IPR013155; KEGG: sta:STHERM_c03870 leucyl-tRNA synthetase; PFAM: Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Arginyl-tRNA synthetase, class Ic, core; SPTR: Leucyl-tRNA synthetase; TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.725
AEJ62121.1
Transglutaminase domain-containing protein; PFAM: Transglutaminase-like superfamily; InterPro IPR002931; KEGG: sta:STHERM_c18220 hypothetical protein; PFAM: Transglutaminase-like; SMART: Transglutaminase-like; SPTR: Transglutaminase domain-containing protein.
       0.713
AEJ62122.1
KEGG: sta:STHERM_c18230 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.710
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
 
 0.672
AEJ62123.1
KEGG: sta:STHERM_c18240 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.661
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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