STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62136.1PFAM: YbbR-like protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: sta:STHERM_c18360 membrane associated protein; PFAM: YbbR-like; SPTR: YbbR family protein. (322 aa)    
Predicted Functional Partners:
dacA
Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
 
  
 0.975
AEJ62134.1
Protein of unknown function DUF2225; PFAM: Uncharacterized protein conserved in bacteria (DUF2225); COGs: COG1655 conserved hypothetical protein; InterPro IPR018708; KEGG: sta:STHERM_c18340 hypothetical protein; PFAM: Protein of unknown function DUF2225; SPTR: Putative uncharacterized protein.
 
     0.867
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
       0.811
AEJ62132.1
Phage SPO1 DNA polymerase-related protein; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122:IPR005273; KEGG: sta:STHERM_c18320 hypothetical protein; PFAM: Uracil-DNA glycosylase-like; SPTR: Phage SPO1 DNA polymerase-related protein; TIGRFAM: Phage SPO1 DNA polymerase-related protein.
       0.811
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
       0.811
acpS
Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.811
AEJ62138.1
Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase; COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: sta:STHERM_c18380 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase.
       0.811
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
       0.653
AEJ62130.1
PFAM: DJ-1/PfpI family; TIGRFAM: DJ-1 family protein; COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR002818:IPR006287; KEGG: sta:STHERM_c18300 hypothetical protein; PFAM: ThiJ/PfpI; SPTR: DJ-1 family protein; TIGRFAM: DJ-1.
       0.588
AEJ62140.1
KEGG: tde:TDE1911 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
       0.553
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.