STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62141.1ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (336 aa)    
Predicted Functional Partners:
AEJ60986.1
PFAM: Dinitrogenase iron-molybdenum cofactor; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: sta:STHERM_c15140 hypothetical protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Putative uncharacterized protein; manually curated.
 
  
 0.899
AEJ61897.1
Soluble ligand binding domain-containing protein; PFAM: SLBB domain; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR019554; KEGG: sta:STHERM_c15850 polysaccharide biosynthesis protein; PFAM: Soluble ligand binding domain; SPTR: Soluble ligand binding domain.
  
 
 0.694
AEJ62142.1
PFAM: Mechanosensitive ion channel; COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: sta:STHERM_c18410 small conductance mechanosensitive ion channel; PFAM: Mechanosensitive ion channel MscS; SPTR: MscS Mechanosensitive ion channel.
       0.603
AEJ62143.1
PFAM: Protein of unknown function (DUF432); KEGG: sta:STHERM_c18420 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.603
AEJ62140.1
KEGG: tde:TDE1911 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
       0.580
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
  
  
 0.543
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
     0.522
AEJ61888.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017475:IPR003362; KEGG: tth:TTC0275 undecaprenyl-phosphate galactosephosphotransferase; PFAM: Bacterial sugar transferase; SPTR: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
  
  
 0.494
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.471
AEJ62144.1
Isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804:IPR004439; KEGG: sta:STHERM_c18430 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; SPTR: Isocitrate dehydrogenase (NADP); TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic.
       0.471
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]