Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62142.1PFAM: Mechanosensitive ion channel; COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: sta:STHERM_c18410 small conductance mechanosensitive ion channel; PFAM: Mechanosensitive ion channel MscS; SPTR: MscS Mechanosensitive ion channel. (300 aa)    
Predicted Functional Partners:
AEJ62143.1
PFAM: Protein of unknown function (DUF432); KEGG: sta:STHERM_c18420 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.899
AEJ62141.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.603
AEJ62144.1
Isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804:IPR004439; KEGG: sta:STHERM_c18430 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; SPTR: Isocitrate dehydrogenase (NADP); TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic.
       0.594
AEJ62140.1
KEGG: tde:TDE1911 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
       0.461
AEJ62145.1
Lipoprotein; KEGG: sta:STHERM_c18440 lipoprotein; SPTR: Putative uncharacterized protein.
       0.429
AEJ62146.1
Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain; LysM domain; InterPro IPR008258:IPR018392:IPR002482; KEGG: sta:STHERM_c18450 transglycosylase, SLT family; PFAM: Lytic transglycosylase-like, catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Lytic transglycosylase catalytic.
       0.429
AEJ62147.1
KEGG: sta:STHERM_c18460 OmpA family protein; SPTR: Putative uncharacterized protein.
       0.429
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
       0.418
AEJ61364.1
Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: sta:STHERM_c10650 K+-dependent Na+/Ca+ exchanger related-protein; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like.
 
     0.413
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.