STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62148.1PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR010182; KEGG: sta:STHERM_c18470 hypothetical protein; PFAM: Peptidase M20; Peptidase M20, dimerisation; SPTR: Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; TIGRFAM: Acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase. (422 aa)    
Predicted Functional Partners:
AEJ62312.1
PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; COGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR005814:IPR004636; KEGG: sta:STHERM_c20050 acetylornithine aminotransferase; PFAM: Aminotransferase class-III; SPTR: Acetylornithine and succinylornithine aminotransferase; TIGRFAM: Acetylornithine/succinylornithine aminotransferase.
  
 
 0.919
dapL
LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.
    
 0.906
AEJ62149.1
PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: uncharacterized protein, YigZ family; COGs: COG1739 conserved hypothetical protein; InterPro IPR001498:IPR015269:IPR015796; KEGG: sta:STHERM_c18480 hypothetical protein; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; Uncharacterised protein family UPF0029, Impact, C-terminal; SPTR: Uncharacterized protein family UPF0029, Impact; TIGRFAM: Uncharacterised protein family UPF0029, Impact.
       0.773
AEJ62150.1
Transcriptional regulator, GntR family with LacI sensor; PFAM: Bacterial regulatory proteins, gntR family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000524:IPR001761; KEGG: sta:STHERM_c18490 transcriptional repressor; PFAM: HTH transcriptional regulator, GntR; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family with LacI sensor.
  
    0.670
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 
 0.541
AEJ62062.1
Amino-acid N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; Amino acid kinase family; TIGRFAM: amino-acid N-acetyltransferase; COGs: COG0548 Acetylglutamate kinase; InterPro IPR010167:IPR001048:IPR000182; KEGG: sta:STHERM_c17320 amino acid acetyltransferase; PFAM: GCN5-related N-acetyltransferase; Aspartate/glutamate/uridylate kinase; SPTR: Amino-acid N-acetyltransferase; TIGRFAM: Amino-acid N-acetyltransferase (ArgA); Belongs to the acetyltransferase family.
  
  
 0.524
AEJ62151.1
PFAM: Glycosyl hydrolases family 43; COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: sta:STHERM_c18500 beta-xylosidase; PFAM: Glycoside hydrolase, family 43; SPTR: Xylan 1,4-beta-xylosidase.
       0.514
AEJ62152.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c18510 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.
       0.514
AEJ62153.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c18520 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.
       0.514
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
 
 0.455
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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